September 2024- The risk of skin cancer, malignant melanoma, now appears to be decreasing in Sweden – at least in those under 50, according to a new study.

“We can see a trend break in young adults around 2015 where the incidence curves are falling,” says first author Hildur Helgadottir, senior consultant and associate professor of oncology at the Department of Oncology-Pathology, Karolinska Institutet.

She and her research colleagues have analyzed data from the Swedish Melanoma Registry and followed melanoma incidence and mortality for different age segments over time. This means that they have compared individuals in a certain age range at one point in time with individuals in the same age range at another point in time.

The results show that the new-onset curves for people over 50 years of age are steadily increasing, but for the age groups younger than 50 years, the new-onset curves started to decrease around 2015.

“This is the first time we see this in Sweden, and we are actually the first European country to report a decline,” says Hildur Helgadottir.

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Introduction of new oncological drugs

In terms of mortality, the curves have also turned downwards for ages up to 59, but not for those over 60. Hildur Helgadottir believes that the decrease in mortality in the younger groups is due both to a reduction in the incidence of the disease and to the introduction of new oncological drugs that have improved the prognosis for the disease. She believes that the fact that mortality is not decreasing in the elderly is because the incidence of the disease is still so high in this group.

“The question is why the risk of melanoma has decreased. We have not directly analyzed the causes in our study, but we have hypotheses about factors that we believe have interacted,” says Hildur Helgadottir.

“The first national ‘Sun Safe’ campaign in the 1990s specifically highlighted the importance of protecting children. About 20 years later, we believe that this has led to a reduction in the incidence of the disease in younger adults,” says Hildur Helgadottir.

Another factor is that access to sunbeds has decreased drastically. Since 2018, there has been an 18-year age limit on sunbeds, but the number of public sunbeds decreased much earlier.

Young people spend more time indoors

Third, mobile phones and computers mean that children and young people are spending more time indoors and are not exposed to sunlight in the same way today.

Finally, immigration means that there are more individuals in Sweden with darker pigmentation who can tolerate the sun better.

The research was funded by the Swedish Regional Cancer Centers, the Swedish Cancer Society, Region Stockholm, and the Research Funds of Radiumhemmet, among others. The researchers report that there are no conflicts of interest.